Search on: LIM KINASES 
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Descriptor English:   Lim Kinases 
Descriptor Spanish:   Quinasas Lim 
Descriptor Portuguese:   Quinases Lim 
Synonyms English:   LIM Kinase
LIM Motif-Containing Protein Kinases
LIM-Kinase
Kinase, LIM
Kinases, Lim
LIM Motif Containing Protein Kinases  
Tree Number:   D08.811.913.696.620.682.700.542
D12.644.360.390
D12.776.476.396
D12.776.512.124
Definition English:   Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52744 
Unique Identifier:   D054461 

Occurrence in VHL: 		 

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